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Table 3 Genotype and allele distribution of ADH1B and ALDH2 in patients with HDS and NHDS

From: The role of ALDH2 and ADH1Bpolymorphism in alcohol consumption and stroke in Han Chinese

Gene

N

Genotype number (frequency)

Allele number (frequency)

  

*1/*1

*1/*2

*2/*2

pValue

*1

*2

pValue

ADH1B

        

   NHDS

83

10 (0.12)

38 (0.46)

35 (0.42)

 

58 (0.35)

108 (0.65)

 

   HDS

65

9 (0.14)

26 (0.40)

30 (0.46)

0.78

44 (0.34)

86 (0.66)

0.84

ALDH2

        

   NHDS

83

45 (0.54)

31 (0.37)

7 (0.08)

 

121 (0.73)

45 (0.27)

 

   HDS

65

61 (0.94)

4 (0.06)

0 (0.00)

< 0.001

126 (0.97)

4 (0.03)

< 0.001

  1. The statistical comparison was evaluated by the Pearson chi-square test