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Table 4 Risk of functional polymorphisms of ADH1B and ALDH2 for HDS

From: The role of ALDH2 and ADH1Bpolymorphism in alcohol consumption and stroke in Han Chinese

Variable

Regression

coefficient

Standard

error

pvalue

Odds

ratio

95%

confidence

interval

ADH1B*1/*2

-0.4196

0.69

0.5428

0.66

0.170-2.539

ADH1B*2/*2

-0.2972

0.70

0.6725

0.74

0.187-2.947

ALDH2*1/*2

-3.5167

1.32

0.0078

0.030

0.002-0.396

ADH1B × ALDH2

0.7031

0.8658

0.4167

  

Constant

1.2854

0.7012

0.0668

  
  1. HDS (n = 65); NHDS (n = 83). Statistical comparison was evaluated by multiple logistic regression after adjustment for hypertension, DM, smoking and liver dysfunction and the rest of the genotypes of ADH1B and ALDH2. The ALDH2*2/*2 genotype was not included for comparison, as no such genotype was found in the HDS group. Reference groups for ADH1B and ALDH2 were ADH1B*1/*1 and ALDH2*1/*1, respectively
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Human Genomics

ISSN: 1479-7364