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Table 4 Neurodevelopmental disorder associations for differentially expressed genes (DEGs)

From: Paternal aging impacts expression and epigenetic markers as early as the first embryonic tissue lineage differentiation

Disease

Overlapping genes

Fold enrichment (odds ratio)

OR 95% confidence interval

P-Value

FDR

APA Inner Cell Mass (ICM)

Autism spectrum disorder

4/1127

0.77

0.21-2.01

0.82

0.82

Schizophrenia

6/2092

0.73

0.22-1.36

0.31

0.73

Bipolar disorder

2/430

1.01

0.12-3.72

0.73

0.82

APA Trophectoderm (TE)

Autism spectrum disorder

8/1127

0.68

0.29-1.37

0.36

0.73

Schizophrenia

18/2092

0.83

0.49-1.34

0.50

0.80

Bipolar disorder

2/430

0.45

0.05-1.65

0.34

0.73

  1. * Indicates significance FDR≤0.05
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Human Genomics

ISSN: 1479-7364