Table 2 Priority cancer chemopreventive agents
From: Mitochondrial and nuclear genomics and the emergence of personalized medicine
Class of agent | Chemical/brand name | Preventive targets |
|---|---|---|
Selective estrogen receptor modulators and other hormonal agents | Tamoxifen | Breast |
Arzoxifene | Breast | |
Acolbifene | Breast | |
Raxoxifene/Evista® | Breast | |
Finasteride | Prostate | |
Nonsteroidal anti- inflammatory drugs | Celecoxib/Celebrex® | Colon, breast, prostate, bladder |
Sulindac/Clinoril® | Esophagus, skin | |
Aspirin | Â | |
Minerals and micronutrients | Calcium compounds | Colon |
Glucocorticoids | Budesonide | Lung |
Retinoids | All-trans-retinoic acid tretinoin/Retin-A® | Cervix, esophagus, larynx, lung, |
|  | 9-cis-Retinoic acid alitretinoin/Panretin® | Nasopharynx, oral cavity, ovary |
|  | 13-cis-Retinoic acid isotreninoin/Accutane® |  |
| Â | 4-Hydroxyretinamide, (4-HPR) fenretinide | Â |