Fig. 2From: Intragraft transcriptional profiling of renal transplant patients with tubular dysfunction reveals mechanisms underlying graft injury and recoveryDistribution of uRBP levels according to glomerular filtration rates and hierarchical clustering analysis of samples from different ranges of uRBP levels. a Histograms showing uRBP values according to eGFR levels at enrollment (t0) and after 12 months of follow-up (t12). uRBP levels are expressed as the mean ± SEM. The estimated glomerular filtration rates (eGFR) were calculated using the MDRD formula. **p < 0.05, **p < 0.001 compared to eGFR at 30–45 mL/min, using ANOVA followed by Tukey’s correction. b Best-fit slope of the linear regression of the delta values from urinary retinol-binding protein (uRBP) levels and eGFR between t0 and t12. The estimated eGFR was calculated using Cockcroft-Gault or MDRD formulas. c Hierarchical clustering analysis of samples in the high group (HG, uRBP levels from 0.4 to 1 mg/L) and very high group (VHG, uRBP ≥ 1 mg/L) at t0 and t12Back to article page