Genetic association of PRKCD and CARD9 polymorphisms with Vogt–Koyanagi–Harada disease in the Chinese Han population

Table 4 Haplotype frequencies of the five tag SNPs within CARD9

Haplotype^a	Case (freq)^b	Control (freq)^b	χ2	Pearson’s P	Pc value	Odds ratio [95%]
A C C C G	97.89 (0.065)	84.72 (0.060)	0.267	0.605	NS	1.083 [0.801–1.462]
A C C C G	102.96 (0.065)	88.40 (0.060)	0.182	0.670	NS	1.066 [0.794–1.430]
A T C C G	1091.84 (0.689)	961.79 (0.651)	2.015	0.156	NS	1.123 [0.957–1.317]
G C C C G	232.01 (0.146)	206.54 (0.140)	0.071	0.790	NS	1.028 [0.839–1.260]
G C T T A	93.29 (0.059)	128.62 (0.087)	10.175	0.001	0.005	0.639 [0.484–0.843]

^a The sequence of the CARD9 tag SNPs (rs4073153, rs9411205, rs3812555, rs59902911, rs11145769)
^bThe frequencies of haplotype were calculated using SHEsis online platform. Haplotypes were selected with minor frequency greater than 0.03

ISSN: 1479-7364