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Fig. 2 | Human Genomics

Fig. 2

From: A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

Fig. 2

Local genetic correlation: BMI-adjusted sex hormone-binding globulin and rheumatoid arthritis (excluding MHC). X-axis represents chromosomes, Y-axis represents negative logarithm of P values, and each dot in the Manhattan plot represents a linkage-disequilibrium independent genomic region. Chromosomes and genomic regions for significant local genetic correlations are marked. MHC regions were excluded due to their complex LD pattern. SHBGadjBMI: sex hormone-binding globulin adjusted for BMI; RA: rheumatoid arthritis

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Human Genomics

ISSN: 1479-7364