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Fig. 4 | Human Genomics

Fig. 4

From: A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

Fig. 4

Causal associations: sex hormone-binding globulin and risk of rheumatoid arthritis in Mendelian randomization. Green squares represent odds ratio of outcomes per each SD increment in genetically predicted exposures. Bars represent 95% confidence intervals. The Mendelian randomization analysis was performed based on the inverse variance weighted approach. SHBG: sex hormone-binding globulin; SHBGadjBMI: sex hormone-binding globulin adjusted for BMI; RA: rheumatoid arthritis; SNP: Single nucleotide polymorphism; OR: odds ratio; CI: confidence interval

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Human Genomics

ISSN: 1479-7364