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Table 1 Genome-wide genetic correlation between sex hormone-binding globulin and rheumatoid arthritis, excluding the MHC region

From: A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis

Trait

\({\text{r}}_{{\text{g}}}\)

SE

Z

P

Overall

SHBGadjBMI

0.11

0.03

3.8

1.0 × 10–4

SHBG

0.05

0.02

2.06

3.9 × 10–2

Men

SHBGadjBMI

0.07

0.02

3.26

1.1 × 10–3

SHBG

0.05

0.02

2.14

3.2 × 10–2

Women

SHBGadjBMI

0.09

0.02

3.71

2.0 × 10–4

SHBG

0.04

0.03

1.65

0.10

  1. \(r_{{\text{g}}}\), Genetic correlation; SE, Standard error; SHBGadjBMI, Sex hormone-binding globulin adjusted for BMI; SHBG, Sex hormone-binding globulin
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Human Genomics

ISSN: 1479-7364