Table 2 Genes with concordant differential expression in transcriptomics and proteomics that are involved in the main biological processes identified via enrichment analysis
Gene | Direction | Biological process | Potential TF |
|---|---|---|---|
AFAP1 | Upregulated | Cytoskeletal processes | SRF |
FMNL2 | Upregulated | Cytoskeletal processes | CREB1 |
FNBP1L | Upregulated | Cytoskeletal processes | CREB1 |
KIF3A | Upregulated | Cytoskeletal processes | – |
MARCKSL1 | Upregulated | Cytoskeletal processes | – |
PLS3 | Upregulated | Cytoskeletal processes | SRF |
ARMC9 | Downregulated | Cytoskeletal processes | SRF |
ARHGEF1 | Downregulated | Cytoskeletal processes | – |
CDC42EP1 | Downregulated | Cytoskeletal processes | – |
IQGAP3 | Downregulated | Cytoskeletal processes | SRF |
PLXNB2 | Downregulated | Cytoskeletal processes | CREB1, SRF |
EIF4G3 | Upregulated | RNA processing | – |
NUDT12 | Upregulated | RNA processing | – |
SART1 | Downregulated | RNA processing | CREB1, SRF |
DDX31 | Downregulated | RNA processing | CREB1, SRF |
DDX54 | Downregulated | RNA processing | SRF |
MYBBP1A | Downregulated | RNA processing | SRF |
NCALD | Upregulated | Vesicular activity | – |
PREPL | Upregulated | Vesicular activity | CREB1 |
TMED1 | Downregulated | Vesicular activity | SRF |
ZFPL1 | Downregulated | Vesicular activity | CREB1, SRF |
AGPAT3 | Downregulated | Metabolism | – |
AACS | Downregulated | Metabolism | CREB1 |
CTBS | Upregulated | Metabolism | – |
DCAKD | Downregulated | Metabolism | CREB1 |
HS2ST1 | Upregulated | Metabolism | – |
ORMDL2 | Downregulated | Metabolism | – |
PCK2 | Downregulated | Metabolism | – |
PI4KB | Downregulated | Metabolism | – |
UAP1L1 | Downregulated | Metabolism | CREB1 |
COMT | Downregulated | Metabolism | CREB1 |