Table 1 GCTA-COJO index SNPs. BETA, SE and P BOLT are the regression statistics of the BOLT-LMM neutrophil count GWAS. BETA, SE and P for META-WOD and META-WD are the regression statistics of the meta-analysed GWAS done on each Kpop, without and with adjustment for the Duffy SNP, respectively, META-N and META-N-Studies indicate the number of meta-analysed individuals in each Kpop, and the number of Kpops included in the meta-analysis
SNP | BETA-BOLT | SE-BOLT | P-BOLT | BETA-META-WOD | BETA-META-WD | META-N | META-N-Studies | CHR | BP (GRCh37) | EA | NEA | EAF |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs2814778 | 0.43 | 0.02 | 2.66E−87 | 0.28 | 0 | 5,793 | 6 | 1 | 159,174,683 | T | C | 0.036 |
rs144109344 | −0.12 | 0.02 | 3.12E−10 | −0.06 | −0.06 | 5,976 | 7 | 2 | 136,787,730 | C | T | 0.964 |
rs530475031 | 0.73 | 0.12 | 3.16E−09 | 0.47 | 0.46 | 4,952 | 5 | 12 | 48,810,860 | G | T | 0.998 |
rs12747038 | −0.22 | 0.04 | 3.89E−09 | −0.13 | −0.08 | 5,976 | 7 | 1 | 146,651,428 | T | G | 0.990 |
rs527921556 | 0.4 | 0.07 | 4.48E−09 | 0.33 | 0.31 | 5,793 | 6 | 6 | 160,605,701 | T | C | 0.996 |
rs557482905 | 0.55 | 0.1 | 5.79E−09 | 0.42 | 0.38 | 3,778 | 4 | 5 | 80,629,499 | C | T | 0.998 |
rs140048432 | −0.33 | 0.06 | 1.11E−08 | −0.25 | −0.25 | 5,976 | 7 | 9 | 17,700,893 | T | C | 0.996 |
rs183362544 | 0.61 | 0.11 | 1.27E−08 | 0.28 | 0.28 | 2,717 | 4 | 2 | 97,045,902 | C | T | 0.998 |
rs558204720 | 0.52 | 0.09 | 1.67E−08 | 0.37 | 0.33 | 1,486 | 2 | 16 | 59,472,815 | T | C | 0.998 |
rs28734019 | −0.65 | 0.12 | 2.89E−08 | −0.53 | −0.5 | 4,124 | 4 | 1 | 90,800,573 | C | T | 0.998 |