Fig. 7
From: Profiling the role of m6A effectors in the regulation of pluripotent reprogramming
Reprogramming-associated m6A modifications in SOX2 and OCT4 gene transcripts. A and C. m6A signal in stem gene transcripts involved in stem cell reprogramming. m6A-IP enrichment signals were the read depth of m6A immunoprecipitation data in human hESC (red), iPSC (fibroblasts fully reprogrammed into iPSC, blue). Transcript regions are depicted as coding exons which are represented by blocks connected by horizontal lines representing introns. B and D. m6A RIP in SOX2 (B) and OCT4 (POU5F1, D). IgG: m6A RIP control group, IP: m6A RIP group