Fig. 3
From: Altered skin microbiome, inflammation, and JAK/STAT signaling in Southeast Asian ichthyosis patients
Microbiome profile in CI patients. A Bacterial community composition at phylum level (Actinobacteria, Firmicutes, Proteobacteria, Bacteroidetes, fungi, and other) represented as average relative abundance from healthy (left) and CI patients (right) and three different skin sites: dry, moist, and sebaceous. B Relative abundance of operational taxonomic units (OTUs) in healthy (left) and CI patients (right) from three different skin sites (dry, moist, and sebaceous) by White’s non-parametric t-test. Circle sizes are proportional to the number of sequences within for the phyla Actinobacteria, Firmicutes, Proteobacteria, Bacteroidetes, fungi, and gram positive/gram negative bacteria. C–M Abundance of specific bacterial species for each CI clinical type: C Cutibacterium acnes; D Lawsonella clevelandensis; E, Bacteroides uniformis; F Bacteroides vulgatus; G Staphylococcus capitis; H Staphylococcus aureus; I Staphylococcus hominis; J Staphylococcus epidermidis; K Moraxella osloensis; L Burkholderia pseudomallei; M Malassezia species. Data expressed as dots with different colors for dry (green), sebaceous (red), and moist (blue) skin with mean ± SD standard error. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001