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Table 1 Characteristics of included GWAS data

From: Mendelian randomization and colocalization analysis reveal novel drug targets for myasthenia gravis

Trait

Consortium

Sample size

Population

Journal

Year

Druggable Genes

/

4479 genes

European

Science Translational Medicine

2017

eQTL

     

 Blood

eQTLGen

31,684 individuals

European

Nature Genetics

2021

pQTL

     

 Plasma proteome

 Plasma proteome

 Plasma proteome

deCODE

/

Pharma Proteomics

4,907 proteins

1,699 proteins

2,923 proteins

European

European

European

Nature Genetics

Nature Genetics

Nature

2021

2020

2023

Disease

     

 Myasthenia Gravis (MG)

 Early-onset MG

 Late-onset MG

IMGGC

IMGGC

IMGGC

38,243 (1873 cases, 36,370 controls)

3,313 (595 cases, 2,718 controls)

34,930 (1,278 cases, 33,652 controls)

European

European

European

PNAS

PNAS

PNAS

2022

2022

2022