Fig. 6

Map of inferred CYP2C8 metabolizer phenotypes Pie charts show the fraction of normal metabolizer (NM, in blue), intermediate metabolizer (IM, in green) and poor metabolizer (NM, in red) for representative countries. IMs and PMs were defined as individuals carrying one or two reduced function alleles, respectively. A, CYP2C8*3 is considered as a normal function allele. B, CYP2C8*3 is considered as a reduced function allele