Table 1 Global frequencies of the most common CYP2C8 alleles
Country | N (participants) | 2 (%) | 3 (%) | 4 (%) |
|---|---|---|---|---|
Africa | ||||
Tanzania | 1089 | 17.3 | 2.3 | 0.6 |
Uganda | 523 | 10.4 | 0 | – |
Madagascar | 153 | 15 | – | – |
Eritrea | 376 | 6 | 4.7 | – |
Nigeria | 220 | 19.1 | 0 | – |
Mali | 206 | 16 | 0 | 0 |
Burkina-Faso | 889 | 18 | 0.4 | 0 |
Senegal | 88 | 22.2 | – | – |
Ghana | 589 | 18 | 0 | 0 |
Botswana | 544 | 11.1 | – | – |
Mozambique | 424 | 16.2 | 4.9 | 0.6 |
South Africa and Zimbabwe | 490 | 14.5 | – | 1 |
Gabon | 48 | 16.7 | – | – |
Congo | 213 | 36.9 | – | – |
Americas | ||||
Mexico | 241 | 0.9 | 7.5 | 4.6 |
USA | 2878 | 2.4 | 7.5 | 2.3 |
Ecuador | 579 | – | 8.1 | – |
Brazil | 1403 | 5.3 | 8.6 | 3.5 |
Bolivia | 129 | – | 3.9 | – |
Europe | ||||
Denmark | 482 | – | 9.9 | – |
Norway | 309 | – | 9.1 | – |
Sweden | 2496 | 0.6 | 9.8 | 5.6 |
Faroese Island | 312 | – | 6.9 | – |
Finland | 5847 | 0.003 | 11.5 | 5.6 |
UK | 219 | 0.4 | 10.8 | 7.5 |
Scotland | 719 | – | 15.1 | – |
Italy | 33 | – | 10.6 | – |
Spain | 933 | 1.6 | 15.8 | 5.1 |
Portugal | 164 | 1.2 | 19.8 | 6.4 |
Russia | 479 | 0 | 8.7 | – |
Czech Republic | 161 | 0.3 | 10.9 | 5.9 |
Bulgaria | 736 | – | 11.2 | – |
Hungary | 826 | – | 8.8 | 3.9 |
Germany | 2827 | – | 10.1 | – |
Netherlands | 96 | – | 9.9 | 4.6 |
Asia | ||||
Malaysia | 258 | 1.9 | 1.9 | 0 |
Cambodia | 75 | – | 0 | – |
China | 1287 | 0.2 | 2 | 1 |
Japan | 1102 | 0 | 0 | 0 |
Korea | 146 | 0 | 0 | 0 |
India | 985 | 1.8 | 3 | 2.4 |
Jordan | 381 | – | 4.3 | 6.6 |
Oceania | ||||
Australia | 210 | – | 8.8 | 3.8 |