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Table 3 Comparison of pedigree-phased haplotypes for nine SNPs over 2 Mb of 17q11-12 in Centre d'Etude Polymorphisme Humain (CEPH) grandparents (n = 87) with MLOCUS estimates from unphased genotype data from these same individuals

From: Characterisation of SNP haplotype structure in chemokine and chemokine receptor genes using CEPH pedigrees and statistical estimation

Haplotype

Count

Frequency

MLOCUS

Similarity index

MSE

111111111

36

0.2069

0.2374

0.0305

0.0009

111111122

22

0.1264

0.1332

0.0067

0.0000

121111111

19

0.1092

0.1450

0.0358

0.0013

211111111

18

0.1034

0.0631

0.0404

0.0016

211111122

9

0.0517

0.0605

0.0088

0.0001

111211111

8

0.0460

0.0245

0.0214

0.0005

111111121

6

0.0345

0.0341

0.0004

0.0000

121122111

5

0.0287

0.0145

0.0143

0.0002

121111121

4

0.0230

0.0198

0.0032

0.0000

121211122

3

0.0172

0.0000

0.0172

0.0003

211122111

3

0.0172

0.0315

0.0143

0.0002

112111122

3

0.0172

0.0168

0.0004

0.0000

112111111

3

0.0172

0.0196

0.0023

0.0000

121111122

3

0.0172

0.0209

0.0037

0.0000

121211111

2

0.0115

0.0051

0.0064

0.0000

212111122

2

0.0115

0.0000

0.0115

0.0001

212111111

2

0.0115

0.0345

0.0230

0.0005

211221211

2

0.0115

0.0165

0.0050

0.0000

211111121

2

0.0115

0.0088

0.0027

0.0000

211211111

2

0.0115

0.0218

0.0103

0.0001

111121211

2

0.0115

0.0000

0.0115

0.0001

122211111

2

0.0115

0.0113

0.0002

0.0000

111122111

2

0.0115

0.0000

0.0115

0.0001

122111122

2

0.0115

0.0000

0.0115

0.0001

111211122

2

0.0115

0.0245

0.0130

0.0002

111111112

1

0.0057

0.0000

0.0057

0.0000

112211111

1

0.0057

0.0000

0.0057

0.0000

121222111

1

0.0057

0.0000

0.0057

0.0000

211211122

1

0.0057

0.0000

0.0057

0.0000

111221211

1

0.0057

0.0000

0.0057

0.0000

121111112

1

0.0057

0.0066

0.0009

0.0000

111222111

1

0.0057

0.0136

0.0078

0.0001

122111111

1

0.0057

0.0000

0.0057

0.0000

211122122

1

0.0057

0.0000

0.0057

0.0000

111121212

1

0.0057

0.0000

0.0057

0.0000

 

174

1.0000

0.9636

0.8196

0.0002

  1. The IF (similarity index) and the mean squared error (MSE) for the two haplotype analyses are indicated at the bottom of the table. Those haplotypes present only in the MLOCUS analysis (less than 1 per cent frequency) are not included.