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Table 6 Estimated D' values generated by two methods for all nine SNPs in the 2 Mb chemokine gene region on chromosome I7ql 1-12 in CEPH grandparents (n = 87)

From: Characterisation of SNP haplotype structure in chemokine and chemokine receptor genes using CEPH pedigrees and statistical estimation

  1. Numbers above the diagonal for each table indicate the pairwise D' value for pairs of SNPs in the CEPH grandparent sample, p values for each test are indicated below the diagonal. Values in the upper table (A) indicate D' values calculated in DnaSP from the pedigree-derived haplotypes. Values in the lower table (B) indicate D'-values calculated using the PAIRWISE program from the MLOCUS haplotype frequency estimates. Those values in boxed cells indicate non-significant results. D' estimates in the lower table denoted in italics indicate differences from the values generated in DnaSP for that particular comparison of loci.