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Table 1 Protein family classification and integrative associative analysis for functional annotation*

From: Update on genome completion and annotations: Protein Information Resource

A. Functional inference of uncharacterised hypothetical proteins

SF034452

TIM-barrel signal transduction protein

SF004961

Metal-dependent hydrolase

SF005928

Nucleotidyltransferase

SF005933

ATPase with chaperone activity and inactive LON protease domain

SF005211

Alpha/beta hydrolase

SF014673

Lipid carrier protein

SF005019

[Ni, Fe]-hydrogenase-3-type complex, membrane protein EhaA

B. Correction, or improvement, of genome annotations

SF025624

Ligand-binding protein with an ACT domain

SF005003

Inactive homologue of metal-dependent protease

SF000378

Glycyl radical cofactor protein YfiD

SF000876

Chemotaxis response regulator methylesterase CheB

SF000881

Thioesterase, type II

SF002845

Bifunctional tetrapyrrole methylase and MazG NTPase

C. Enhanced understanding of structure, function and evolutionary Relationships

SF005965

Chorismate mutase, AroH class

SF001501

Chorismate mutase, AroQ class, prokaryotic type

  1. *PIRSF protein family reports detail supporting evidence for both experimentally validated and computationally predicted annotations.