Figure 2

UPGMA tree and possible family and subfamily divisions of the Caenorhabditis elegans cyclophilin gene family, based on evolutionary divergence. The root of cyn-, is acceptable because it has not yet been used by any other gene database, except 'cyclone' in mouse. Families are designated by Arabic numerals and represent amino acid identity of 40 per cent or greater. Subfamilies are designated by letters and represent amino acid identity of 54 per cent or greater. Individual genes within subfamilies are then given Arabic numbers. Identifiers are the WormPep accession numbers.