Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Table 3 Distribution of χ² test scores in SNPs selected for individual genotyping.

	All SNPs	Conforming^a	Non-conforming^b
Selected SNPs	284	142	142
Number meeting quality criteria	263	135	128
p < 0.04^c	90	59	31
p < 0.01^c	41	24	17

^a SNPs selected based on corroborating evidence from the haplotype-fitting procedure.
^b SNPs selected based on a large $Δ \hat{p}$ but without supporting haplotype information.
^c SNPs meeting this threshold in a χ² test of allelic association with the HDL phenotype.
SNPs, single nucleotide polymorphisms.

ISSN: 1479-7364