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Table 4 SNPs having significant association with HDL cholesterol in the study population.

From: Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Chromosome

Positiona

dbSNP

refLb

altL

refH

altH

Δpc

χ 2

pvalue

16

56729856

rs1800775

392

196

288

322

0.193

46.2

1.1 × 10-11

16

56730908

rs708272

446

234

318

320

0.151

33.5

7.2 × 10-9

16

56730831

rs711752

451

239

314

312

0.165

31.2

2.4 × 10-8

16

56733948

rs11508026

441

227

303

289

0.167

28.6

9.1 × 10-8

16

56739509

rs7205804

436

244

312

318

0.146

28.4

9.7 × 10-8

16

56740998

rs11076175

535

155

563

73

-0.101

28.1

1.2 × 10-7

  1. a Position on GenBank sequence NC_000016.4.
  2. b Counts of reference and alternate alleles for low and high HDL cholesterol groups.
  3. c Allele frequency difference, calculated as refL /(refL + altL) - refH /(refH + altH).
  4. dbSNPs single nucleotide polymorphism database; HDL, high-density lipoprotein.