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Table 5 Genotyping results for 14 CETP gene SNPs in the test and replicate samples.

From: Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels

Positiona dbSNP Study samples Replicate samples Overall pvalueb
   Δp pvalue Odds ratioc Δp pvalue Odds ratio  
56729658 rs4783962 0.060 1.2 × 10-2 1.38 0.100 2.8 × 10-2 1.87 1. 4 × 10-3
56729856 rs1800775 0.193 1.1 × 10-11 2.26 0.104 1.5 × 10-1 1.40 1. 8 × 10-11
56730831 rs711752 0.165 2.4 × 10 -8 1.88 0.208 5.0 × 10 -4 2.21 5.9 × 10 -11
56730908 rs708272 0.151 7.2 × 10 -9 1.92 0.202 3.2 × 10 -4 2.25 1.2 × 10 -11
56733948 rs11508026 0.167 9.0 × 10 -8 1.85 0.186 1.9 × 10 -3 2.06 7.1 × 10 -10
56739509 rs7205804 0.146 9.7 × 10 -8 1.82 0.142 5.6 × 10 -3 1.89 1.9 × 10 -9
56740998 rs11076175 -0.101 1.2 × 10-7 0.45 -0.006 8.9 × 10-1 0.96 1.6 × 10-6
56743996 rs289716 -0.060 1.6 × 10-2 0.75 -0.039 3.9 × 10-1 0.81 1.1 × 10-2
56745805 rs4784744 -0.075 5.0 × 10-3 0.72 -0.157 8.7 × 10-3 0.53 2.4 × 10-4
56750165 rs1800774 0.009 7.5 × 10-1 1.04 0.102 5.8 × 10-2 1.53 2.5 × 10-1
56750712 rs5882 -0.073 4.4 × 10-3 0.72 -0.017 8.0 × 10-1 0.94 7.7 × 10-3
56751939 rs1800777 -0.041 1.1 × 10-3 0.33 -0.009 2.9 × 10-1 1.06 4.2 × 10-3
56752282 rs1801706 0.029 2.0 × 10-1 1.20 -0.022 2.9 × 10-1 0.73 5.0 × 10-1
56752382 rs289742 -0.023 1.2 × 10-1 0.76 -0.053 4.6 × 10-2 0.40 3.0 × 10-1
  1. a Position on GenBank sequence NC_000016.4.
  2. b Calculated from a χ2 test for the combined study and replicate samples.
  3. c Calculated as (refL /altL)/(refH /altH), where these are allele counts as in Table 4.
  4. SNPs in bold are those with significant association with HDL cholesterol in both the study and replicate populations.
  5. CETP, cholesteryl ester transfer protein dbSNP, single nucleotide polymorphism database; HDL, high-density lipoprotein.