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Figure 3 | Human Genomics

Figure 3

From: Comparison of regional gene expression differences in the brains of the domestic dog and human

Figure 3

Volcano plots of significance against fold change in transcript abundance for the indicated contrasts. For example, each point in the top left panel shows the difference in log2 mean expression level for cerebellum minus cortex, so that genes more highly expressed in the cortex are to the left. Plus or minus 1 correspond to twofold differences. Higher significance is towards the top on a scale of the negative logarithm of the p-value, with the p < 0.0001 cut-off indicated by a light horizontal line on each panel. Note that a large number of genes is differentially expressed in each brain region, but that relatively few genes differentiate the breeds.

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