Table 1 Estimated false-positive rates for the different statistical tests
From: Trick or treat: The effect of placebo on the power of pharmacogenetic association studies
Number of persons | False-positive rates | ||||
|---|---|---|---|---|---|
Direct association | Indirect association | ||||
Single marker | Haplotype | ||||
Categories | Random | ||||
500 | 0.045 | M = 3 | 0.06 | 0.06 | 0.051 |
M = 5 | 0.03 | 0.08 | 0.039 | ||
1,000 | 0.042 | M = 3 | 0.04 | 0.05 | 0.046 |
M = 5 | 0.06 | 0.01 | 0.04 | ||