Genome-wide scans for loci under selection in humans

Table 2 Summary of genome-wide scans for selection

Data	Number of loci	Statistical method	Comments	Reference
SNP	26,530 markers	Population structure	174 candidate selection genes were Identified whose levels of population structure were inconsistent with neutrality	[65]
Microsatellite	5,257 markers	Intraspecific polymorphism	43 sliding windows were identified that contained significant deficits in heterozygosity relative to neutral expectations	[66]
Microsatellite	332 markers	Population structure	15 loci were identified with levels of population structure inconsistent with neutrality	[67]
Microsatellite	624 markers	Population structure	13 loci were identified with levels of population structure inconsistent with neutrality	[68]
DNA sequence	7,645 genes	Interspecific divergence	1,547 genes with d_n/d_s > 1 in the human lineage	[62]

SNP = single nucleotide polymorphism; d_n = number of non-synonymous amino acid substitutions in a gene; d_s = number of synonymous amino acid substitutions in a gene.

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