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Table 3 McDonald-Kreitman test comparing levels of human polymorphism and divergence between human and chimpanzee at conserved versus non-conserved sites across distantly related mammals.

From: Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons

 

Non-conserveda

Conserved

Rare polymorphic sites

  

Fixed

19

5

Polymorphicb

11

4

Common polymorphic sites

  

Fixed

19

5

Polymorphic

1

4

  1. a If the allele in chimpanzee (ancestral) was identical to that found in the same position in rodent, artiodactyl and carnivore, the site was considered conserved across three lineages.
  2. b The singleton indel was not included in this analysis.