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Table 1 Summary of the results.

From: Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

 

n

Genes

 

   Carcinogenesis-related genes

2,832

Expressed in breast tissue

981

With validated nsSNPs

189

With functional nsSNPs

75

nsSNPs

 

   Validated nsSNPs

367

Benign by PolyPhen

258

Functional by PolyPhen

109

With ≥ 5% minor allele frequency

67

With < 5% minor allele frequency

42

  1. Abbreviation: n = number; nsSNP = non-synonymous form of single nucleotide polymorphisms. Please note that only the genes and the nsSNPs for which a reliable PolyPhen prediction (based on ≥ 5 proteins in the alignment) was available are shown in this table.