Table 1 Determinants of power in genome-wide association and expression studies.
From: Detecting multiple associations in genome-wide studies
| Â | Genetic association study | Gene expression study |
|---|---|---|
Number of genes tested | High | High |
Number k of true effects | Few;1 <k < 50 | Moderate;k >>1 |
Sample size | Large; thousands | Small; tens |
Gene effect size | Low; odds ratio <2 | High; logfold-change >2 |