Table 1 Three-locus penetrance table where values in bold indicate genotype frequencies and table values indicate penetrance.

From: Multifactor dimensionality reduction: An analysis strategy for modelling and detecting gene - gene interactions in human genetics and pharmacogenomics studies

h² = 0.03			CC			Cc			cc
			0.64			0.32			0.04
		BB	Bb	bb	BB	Bb	bb	BB	Bb	bb
		0.64	0.32	0.04	0.64	0.32	0.04	0.64	0.32	0.04
AA	0.64	0.07	0.02	0.01	0.00	0.08	0.07	0.04	0.02	0.00
Aa	0.32	0.00	0.07	0.06	0.09	0.03	0.08	0.06	0.07	0.01
aa	0.04	0.05	0.01	0.08	0.06	0.01	0.10	0.10	0.02	0.05

Penetrance is probability of disease given a particular genotype combination.

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ISSN: 1479-7364

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