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Table 1 The power of our method for different simulated models (five, ten or 20 disease loci, 1,180 or 590 sibling pairs, relative risk (RR) of 2 or 3) different levels of enrichment for true loci and different levels of significance.

From: Testing groups of genomic locations for enrichment in disease loci using linkage scan data: A method for hypothesis testing

# Real
loci
Group
composition
Power: 1,180
sibling pairs,
RR = 3%
Power:1,180
sibling pairs,
RR = 2%
Power: 590
sibling pairs,
RR = 3%
Power: 590
sibling pairs,
RR = 2%
  Real loci False α = 0.05 α = 0.01 α = 0.05 α = 0.01 α = 0.05 α = 0.01 α = 0.05 α = 0.01
  5 0 100 100 100 92 100 96 100 84
  5 3 100 98 90 71 94 88 80 51
  5 5 99 94 81 58 93 79 70 40
5 5 10 95 76 69 42 84 58 53 25
  3 0 100 95 88 72 97 88 82 52
  3 2 94 78 71 43 84 61 57 30
  3 5 80 52 54 27 67 37 38 16
  10 0 100 100 100 92 100 92 72 48
  10 5 99 92 89 63 88 64 54 29
  10 10 94 77 78 48 75 48 46 22
  10 20 80 54 58 30 60 30 35 14
10 5 0 90 72 75 48 77 44 48 20
  5 3 75 49 56 28 53 26 32 13
  5 5 68 42 49 24 47 21 29 11
  5 10 53 28 35 15 35 16 22 7
  20 0 100 76 68 44 65 35 32 12
  20 10 80 49 56 31 47 23 26 10
  20 20 67 37 47 21 40 18 24 10
  20 40 49 24 36 16 31 14 17 6
  15 0 84 58 61 35 53 26 29 13
20 15 10 64 34 45 20 40 16 23 9
  15 20 51 23 36 15 29 13 18 7
  15 30 41 19 29 12 26 9 14 5
  10 0 67 40 47 23 41 18 25 9
  10 5 51 24 38 15 32 13 19 6
  10 10 41 19 31 11 26 9 16 6
  10 15 35 14 24 9 23 8 15 5