Genetic factors leading to chronic Epstein-Barr virus infection and nasopharyngeal carcinoma in South East China: Study design, methods and feasibility

Table 4 Significant allele frequencies between NPC versus IgA⁺ groups.

cM*	Locus	Individuals#			Allele freq(%)			Dominant			Recessive
		Allele	NPC	IgA+	NPC		IgA+	OR	p value	95% CI	OR	pvalue	95% CI
37.64	D4S2950	141	334	270	12.9	<	19.6	0.70	0.06	0.48-1.01	0.30	0.02	0.11-0.84
37.74	D4S3040	213	324	261	17.4	>	14.0	1.52	0.03	1.04-2.22	1.47	0.42	0.57-3.75
37.74	D4S3040	215	324	261	15.6	>	12.5	1.21	0.34	0.82-1.79	5.36	0.03	1.17-24.53
41.57	D4S2974	135	347	281	60.7	<	64.9	1.22	0.41	0.76-1.97	0.67	0.02	0.48-0.93
41.57	D4S2974	137	347	281	16.9	>	11.4	1.51	0.03	1.03-2.20	3.43	0.07	0.92-12.85
43.27	D4S3357	271	340	271	29.7	<	33.4	0.71	0.04	0.51-0.99	1.01	0.98	0.60-1.71
43.33	D4S350	256	346	275	64.6	>	58.7	1.61	0.05	1.01-2.56	1.24	0.21	0.89-1.7
44.11	D4S1547	251	349	276	56.4	>	52.7	0.91	0.64	0.62-1.35	1.53	0.02	1.07-2.19
44.28	D4S2295	222	345	278	76.1	<	81.3	0.52	0.12	0.23-1.19	0.71	0.05	0.50-1.0
45.71	D4S2381	277	347	277	61.8	<	65.9	0.59	0.03	0.36-0.95	0.92	0.60	0.66-1.28
53.64	D4S2971	165	344	275	45.1	>	43.3	1.43	0.05	1.0-2.05	0.76	0.20	0.50-1.1
55.73	D4S2916	204	336	265	13.8	>	10.6	1.55	0.03	1.03-2.33	0.57	0.39	0.16-2.07

Abbreviations: CI, confidence interval; cM, centimorgan; IgA, immunoglobulin A; NPC, nasopharyngeal carcinoma; OR, odds ratio.
* See Figure 1.

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