From DNA to RNA to disease and back: The 'central dogma' of regulatory disease variation

Table 1 Genes with non-coding variants affecting disease

Gene	Disease	Reference
CAT	Hypertension	[12]
CCR5	HIV-1 progression and transmission	[13, 14]
CD209	Dengue fever	[15]
CRP	Cardiovascular disease risk	[16]
CTLA4	Autoimmune disease	[9]
DARC	Malaria susceptibility	[10]
DAT1	Attention deficit hyperactivity disorder	[17]
FCRL3	Rheumatoid arthritis and autoimmune disease	[18]
GSK3B	Parkinson's disease	[19]
IGFBP3	Breast cancer	[20]
INS	Type I diabetes	[21]
IPF1	Type II diabetes	[22]
MMP-1	Breast cancer progression	[23]
MMP-3	Coronary artery disease	[24, 25]
NFKB1	Inflammatory bowel disease	[26]
RET	Hirschsprung's disease	[27, 28]
SMYD3	Colorectal cancer, breast cancer, hepatocellular carcinoma	[11]
TNF	Malaria	[29]

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