Figure 1

Illustration of copy number differences between two homologous chromosomes (A and B). Coloured boxes indicate copy number changes, including tandem duplication (red) and two types of deletions: deletion of a tandem segment (green) and deletion of an interspersed segment (blue). Below the chromosomes is a line graph showing the results of a comparison of chromosome B with chromosome A. This is an idealised output of the results that could be obtained from a high-resolution comparative genomic hybridisation experiment.