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Table 1 The incidence of the CYP2C19 genotype and predicted phenotype in the Iruna, Tufi and Fly River regions of Papua New Guinea.

From: A high incidence of polymorphic CYP2C19variants in archival blood samples from Papua New Guinea

Genotype

Frequency (n)

Predicted phenotype

Incidence (%)

c.681

c.636

 

Iruna

Tufi

Fly River

 

Iruna

Tufi

Fly River

G/G

G/G

*1/*1

3

0

1

Extensive metaboliser

6.4

0

12.5

G/A

G/G

*1/*2

9

2

2

Intermediate metaboliser

44.7

30

25

G/G

G/A

*1/*3

12

1

0

    

G/A

G/A

*2/*3

10

5

3

Poor metaboliser

48.9

70

62.5

A/A

G/G

*2/*2

8

2

2

    

G/G

A/A

*3/*3

5

0

0

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