Skip to main content

Table 2 Venous blood acetaldehyde concentrations in male adults with different ADH and ALDH genotypes after alcohol ingestion

From: Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2on blood acetaldehyde concentrations

Ethanol
dose (g/kg)
Combinatorial genotype Subject
number
Mean peak
acetaldehyde
 
  ALDH2 ADH1B (n) (μM) Author
0.2 *1/*1 *2/*2 6 1.0 Peng et al.[29]
0.2 *1/*2 *2/*2 6 24 Peng et al.[29]
0.2 *2/*2 *2/*2 6 75 Peng et al.[29]
0.3 *1/*1 *1/*1 6 0.3 Peng et al.[30]
0.3 *1/*1 *2/*2 6 0.2 Peng et al.[30]
0.3 *1/*2 *1/*1 6 60 Peng et al.[30]
0.3 *1/*2 *2/*2 6 60 Peng et al.[30]
0.4 *1/*1 *1/*1 5 3.3 Mizoi et al.[36]
0.4 *1/*1 *1/*2 8 4.8 Mizoi et al.[36]
0.4 *1/*1 *2/*2 20 4.2 Mizoi et al.[36]
0.4 *1/*2 *1/*1 4 23 Mizoi et al.[36]
0.4 *1/*2 *1/*2 9 23 Mizoi et al.[36]
0.4 *1/*2 *2/*2 16 24 Mizoi et al.[36]
0.4 *2/*2 *2/*2 6 79 Mizoi et al.[36]
0.5 *1/*1 *1/*1 8 3.3 Peng et al.[31]
0.5 *1/*1 *2/*2 8 4.0 Peng et al.[31]
0.5 *1/*2 *2/*2 16 76 Peng et al.[31]
0.5 *2/*2 *2/*2 1a 125 Chen et al.[21]
  1. aAn alcohol-dependent patient with normal liver function.
  2. Abbreviations: ADH, alcohol dehydrogenase; ALDH, aldehyde dehydrogenase