Table 1 Genes overlapping linkage and association analyses for carboplatin

1p36.32-36.22

6-23

1.64 (15)

10

69

1p21.1-p13.1

137-150

1.75 (144)

10

130

2q33.3-q36.3

203-228

3.28 (220)

IC₅₀

127

4q27-q32.1

127-157

1.66 (133)

80

118

5q14.3-q22.1

95-116

1.88 (112)

80

63

8q22.2-q24.21

114-136

1.56 (128)

IC₅₀

92

BAALC; rs2201369 (9.12 × 10^-11)

Neuroectoderm/haematopoietic development

8q24.13-q24.22

158-170

2.09 (169)

80

26

158-170

1.87 (169)

IC₅₀

26

C8orf76; rs17378130 (1.48 × 10^-5)

154-170

1.65 (165)

20

30

155-170

1.61 (168)

40

27

9q31.3-q33.3

118-136

1.59 (126)

80

122

118-134

1.58 (126)

40

84

11p13-p12

42-53

2.54 (46)

IC₅₀

23

CD44; rs7116432 (1.51 × 10^-6)

Cell adhesion

LRRC4C; rs4375425 (3.24 × 10^-7)

G protein-mediated signalling, cell adhesion

DKFZP586H2123; rs17727535 (3.63 × 10^-12)

Serine protease

11q14.3-q23.3

91-113

3.36 (99)

IC₅₀

151

CNTN5; rs1441382 (2.57 × 10^-7)

Cell adhesion

IGSF4; rs11215437 (2.82 × 10^-7)

Cell adhesion

PAK1; rs478134 (1.07 × 10^-5)

Protein serine/threonine kinase activity

94-117

1.57 (109)

10

208

14q21.2-q24.1

51-80

1.64 (66)

10

134