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Figure 1 | Human Genomics

Figure 1

From: Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

Figure 1

N-acetyltransferase 2 haplotypes constructed from sequence and genotype data from the total population studied ( n = 127). (a) Linkage disequilibrium plot with the genomic positions indicated at the top. In yellow are the tag single nucleotide polymorphisms (SNPs) which define the major known haplotypes and are able to capture other SNPs within the same haplotype. The amino acid changes at the various positions are shown. (b) Haplotype frequencies. Haplotypes and phenotypes (acetylators) were assigned according to Consensus Arylamine N-Acetyltransferase (NAT) Gene Nomenclature [31].

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