Table S5 Polymerase chain reaction and sequencing primers

CYP2C9

5' UTR

cyp2C9- 5'FLF ATCCTCAACTCAGTATGTCAGC

cyp2C9- 5'FLSF1 ATCCTCAACTCAGTATGTCAGC

cyp2C9-5'FLR ATCACCTAGGTCCACTATATGC

cyp2C9- 5'FLSR1 ACCTTTACCATTAAACCCCC

cyp2C9- 5'FLSF2 CAATTCCTGCCTTCAGGA

cyp2C9- 5'FLSR2 AAGGACTTTGACCCACTGAT

1

cyp2C9-1F GGAATGTACAGAGTGGACAATGG

cyp2C9-1R GATCCCACAATACCTTACCATTTAC

2&3

cyp2C9-2&3F

GACCTGCTGAATATGTTGATGTG

cyp2C9- 2SF TCTTGAACTCCTGACCTTGT

cyp2C9-2&3R CCCGCTTCACATGAGCTAAC

cyp2C9- 2SR GGAGCTCTGTAAGTCTCTGT

cyp2C9- 3SF AGGAGTTTTCTGGAAGAGG

cyp2C9- 3SR GGAAAAACACTGCTCTTTAACTC

4*

cyp2C9-4F CAGCTAGGTTGTAATGGTCAACTC

***

cyp2C9-4R GCTAATGGGCTTAGAAATCAGG

5*

cyp2C9-5F TCATCTGGTTAGAATTGATCCTCTG

***

cyp2C9-5R GCTATTAACTACCGCCTCAACTTC

6*

cyp2C9-6F GAGGAAATGGACCTAGAGACCTTC

***

cyp2C9-6R CCCATTGTAATCACCATTAGTTTG

7*

cyp2C9-7F GTGCATCTGTAACCATCCTCTCT

***

cyp2C9-7R

CAGACACTAGGACCTGTTACAAACC

8*

cyp2C9-8F AGAAGGTTGCATCCAAGTATCC

***

cyp2C9-8R GAGTTCTTGGGTACCTCACTGGT

9

cyp2c9-9F CTCATCCATCCATTCATTCATG

cyp2c9-9SF CTCATCCATCCATTCATTCATG

cyp2c9-9R CTCTAACACTCACCCAAAATAGC

cyp2c9-9SR CGAATGTTCACTAGATCTTCAG

cyp2c9-9S2F CTGCAGCTCTCTTTCCTC

cyp2c9-9S2FR CTCTAACACTCACCCAAAATAGC

CYP2C19

1

cyp2C19-1F CAATTATGACGGTGCATTGG

***

cyp2C19-1R CACTTCCCTTACTGTTTACCCTCA

2&3

cyp2C19-2&3F

cyp2C19-2SF AATTCAGAAATATTTGAGCCTGTGTG

GTTCTTGAAGCTGGGTATTTGTC

cyp2C19-2SR GGTTTTTCTCAACTCCTCCACAA

cyp2C19-2&3R

cyp2C19-3SF GCCTGGGATCTCCCTCCTAGTTT

AGCAAAGTTCAGGAGAACATAGG

cyp2C19-2&3R AAGCAAAGTTCAGGAGAACATAGG

4

cyp2C19-4F

***

CAGCTAGGCTGTAATTGTTAATTCG

cyp2C19-4R

GAGTAATGGAAGACTCCAAAGTGC

5

cyp2C19-5F TTCAATTTCAGAGGCTGCTTG

***

cyp2C19-5R

CTATGATGCTTACTGGATATTCATGC

6

cyp2C19-6F

***

CAGCATATAAACAGAGCCAAAGAC

cyp2C19-6R

ACACCATTAAATTGGGACAGATTAC

7

cyp2C19-7F

***

CCTAGCTTAAGGCACAGTTACACA

cyp2C19-7R

GAAAGACTCAAGGTGTCAAGATGTC

8

cyp2C19-8F

***

GCCTTAAGCTCATGCCTCTTATTAC

cyp2C19-8R

GGCAGAATTCAACCAACCTATACTT

9

cyp2C19-9F TCATTGTTTAGTTGCCTATCCATC

***

cyp2C19-9R CCATCTTCACCTTTGTCCTTTC

CYP2D6

1&2

cyp2D6ex1_2FACCAGGCCCCTCCACCGG

CYP2D6ex1_2FACCAGGCCCCTCCACCGG

cyp2D6ex1_2RCTCTCTGCCCAGCTCGG

cyp2D6ex1SR

GTTTCACCCACCACCCATGTTT

cyp2D6ex2SF

CTTCCACCTGCTCACTCCTGGTA

cyp2D6ex2SR

CCTCCCTAGTGCAGGTGGTTTCT

3&4

cyp2D6ex3_4FATTTCCCAGCTGGAATCC

cyp2D6ex3_4SF

GAGCATAGGGTTGGAGTGGGTG

cyp2D6ex3_4RGAGACTCCTCGGTCTCTC

cyp2D6ex3_4RGAGACTCCTCGGTCTCTC

5&6

cyp2D6ex5_6FGCCTGAGACTTGTCCAGG

cyp2D6ex5_6FGCCTGAGACTTGTCCAGG

cyp2D6ex5_6RCCGGCCCTGACACTCCTTCT

cyp2D6ex5_6RCCGGCCCTGACACTCCTTCT

7,8,9

cyp2D6ex7_9FGGATCCTGTAAGCCTGACCTC

cyp2D6ex7_9FGGATCCTGTAAGCCTGACCTC

cyp2D6ex7_9R

cyp2D6ex7SR

ACTGAGCCCTGGGAGGTAGGTAG

GTGGTGGCATTGAGGACTAGGTG

cyp2D6ex8SF

GTCCAGAGTATAGGCAGGGCTGG

cyp2D6ex8SR

AGCACAAAGCTCATAGGGGGATG

cyp2D6ex9SF

CTTCCTCTTCTTCACCTCCCTGC

cyp2D6ex9SR

AATATGGGCCTCCAGGCTGAGT

NAT2

2

NAT2ex2FGAAGCATATTTTGAAAGAATTGG

NAT2ex2FGAAGCATATTTTGAAAGAATTGG

NAT2ex2RGCATTTTAAGGATGGCCTGT

NAT2SF1 TGCCAAAGAAGAAACACCAA

NAT2SR2 ACCTCGAACAATTGAAGATTTTGA

NAT2ex2RGCATTTTAAGGATGGCCTGT