From: Association of ADHIB and ALDH2gene polymorphisms with alcohol dependence: A pilot study from India
Population characteristic | Mean ± SD (n= 174) | ALDH2(Glu487Lys) genotype | p | ||
---|---|---|---|---|---|
 |  | *1/*1 (n= 128) | *1/*2 (n= 27) | *2/*2 (n= 19) | *1/*1 vs. *2/*2 |
Quantity of alcohol consumed (g/day) | Â | 200 - 400 | 130 - 200 | 30 - 50 | Â |
Age at first use of alcohol (years) | 21.2 ± 5.89 | 20.27 ± 6.54 | 20.14 ± 6.12 | 23.87 ± 3.833 | 0.067 |
Duration of alcohol use (years) | 14.8 ± 9.36 | 17.00 ± 12.11 | 12.42 ± 3.69 | 12.75 ± 6.11 | 0.194 |
Duration of dependence (years) | 7.53 ± 7.19 | 10.33 ± 8.44 | 6.07 ± 5.23 | 3.56 ± 3.31 | <0.0la |
Age at onset of dependence (years) | 25.9 ± 8.17 | 22.33 ± 4.70 | 26.5 ± 8.27 | 32.06 ± 10.12 | <0.0la |
Duration of alcohol use prior to development of dependence (years) | 7.3 ± 5.99 | 6.67 ± 6.99 | 6.36 ± 3.17 | 9.19 ± 6.09 | 0.33 |
SGOT (IU) | 58.38 ± 63.92 | 66.63 ± 75.51 | 56.93 ± 53.38 | 36.12 ± 16.72 | 0.0lla |
SGPT (IU) | 47.23 ± 53.09 | 54.04 ± 65.60 | 42.18 ± 30.24 | 32.68 ± 20.95 | 0.041a |
Total protein (g%) | 0.62 ± 0.16 | 0.59 ± 0.16 | 0.64 ± 0.08 | 0.64 ± 0.22 | 0.45 |
Albumin (g%) | 6.9 ± 0.71 | 6.88 ± 0.73 | 6.84 ± 0.84 | 7.08 ± 0.51 | 0.20 |
Bilirubin total (mg%) | 4.65 ± 5.33 | 4.09 ± 0.49 | 6.88 ± 11.78 | 4.04 ± 0.44 | 0.69 |