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Figure 3 | Human Genomics

Figure 3

From: A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease

Figure 3

Prediction evaluation with USF1 ChIP-chip results from the ENCODE regions. There are 16,405 loci on the ENCODE microarray with potential USF1-BSs identified by the PWM scoring method. Among them, 34 positive and 177 negative loci were used to construct the training dataset for developing the prediction method (see Methods). The remaining 16,194 loci were used as an independent testing dataset. Our prediction method divided these unclassified loci into two groups: predicted positive loci (1,615) with predicted USF1-BSs, and predicted negative loci (14,579) without predicted USF1-BSs. The data are represented as histograms of frequency at intervals of 0.1 log2-ratio of intensities.

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Human Genomics

ISSN: 1479-7364