Pharmacogenetics of antidepressant response: An update

Table 5 Relevant pharmacogenetics association studies that focused on monoamine oxidase-A (MAO-A)

Reference	Gene	Drug	Sample	Outcome measure	Results	p-value
[59]	MAO-A	Various	134 nuclear families (probands affected by bipolar (n = 103) or major depressive (n = 58) disorders)	Transmission disequilibrium test	No association	Not significant
[48]	MAO-A	Fluoxetine	96 MDD patients	CGI	Significant association	0.03 < p <0.05
[60]	MAO-A	Fluvoxamine, paroxetine	248 MDD 195 BPD	HAMD	No association	Not significant

Abbreviations: MDD, major depressive disorder; MAO-A, monoamine oxidase A; BPD, bipolar disorder; CGI, Clinical Global Impression Scale; HAMD, Hamilton Rating Scale for Depression

ISSN: 1479-7364