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Table 3 Genomic and transcriptomic variations in annotated human AKRs

From: Aldo-keto reductase (AKR) superfamily: Genomics and annotation

AKR Gene IDa Chromosomal location No. of SNPsb (in gene/coding region/non-synonymous/frameshift) SNP frequency (per 1 kilobase: in gene/in coding region) Peptide variants Additional processed transcripts Pseudogenes on vega (HGNC)
1A1 10327 1p33-p32 154/9/5/1 8.01/9.2 3 10 0
1B1 231 7q35 160/13/9/0 9.53/13.67 3 12 5(8)
1B10 57016 7q33 127/16/5/0 9.65/16.82 1 3 4
1C1 1645 10p15-p14 160/16/6/0 10.88/16.46 3 2 0
1C2 1646 10p15-p14 353/16/8/0 12.5/16.46 1 1 0
1C3 8644 10p15-p14 261/23/13/2 19.61/23.66 1 3 0
1C4 1109 10p15 -p14 198/7/6/0 8.95/7.2 1 1 0
1D1 6718 7q32-q33 275/1/0/0 6.57/1.02 4 2 2(1)
1E2 83592 10p15.1 211/12/7/0 9.66/12.46 2 4 0
6A3 7881 3q26.1 1888/1/0/0 4.51/0.81 10 0 0
6A5 8514 1p36.3 414/8/2/1 7.15/7.25 8 6 0
6A9 9196 17p13.1 42/3/1/2 6.24/2.47 1 2 0
7A2 8574 1p36.13 71/10/8/0 8.68/9.26 1 0 4
7A3 22977 1p36.13 67/12/5/0 10.76/12.05 1 0 0
  1. aAt NCBI (http://www.ncbi.nlm.nih.gov).
  2. bDeduced from the vega database (http://vega.sanger.ac.uk/index.html).
  3. The table does not include the putative transcript variants and pseudogenes listed in Table 2.