Identifying positive selection candidate loci for high-altitude adaptation in Andean populations

Table 4 Summary of the significant core regions containing known genes in the Andean population for the WGLRH test

Chromosome	SNPs in core region	Haplotype frequency	p-value adjusted	Genes in core region*
1	3	0.060	0.032	KCNK2
1	2	0.080	0.038	KCNK2
1	5	0.070	0.050	KIAA1026
1	7	0.070	0.032	PEX14
2	2	0.520	0.016	ERBB4
2	2	0.540	0.006	INPP5D
2	2	0.080	0.038	TMEM169
3	2	0.330	0.011	CPNE4
4	2	0.051	0.007	LDB2
4	3	0.090	0.000	RBM47
5	7	0.070	0.034	FCHO2
6	3	0.120	0.018	F13A1
6	4	0.080	0.001	F13A1
6	3	0.120	0.036	KCNK5
8	2	0.130	0.036	ADRA1A
9	2	0.176	0.047	ADAMTSL1
9	2	0.610	0.044	PTPRD
9	3	0.070	0.011	VAV2
10	2	0.170	0.015	AK056561
10	2	0.500	0.021	FAM107B
10	2	0.101	0.040	GFRA1
10	3	0.540	0.023	OLAH
11	2	0.090	0.047	LDLRAD3
11	3	0.060	0.002	PSMD13
12	2	0.330	0.032	CHST11
12	5	0.080	0.035	SLC4A8
14	7	0.080	0.002	KCNK10
14	3	0.440	0.043	PPP2R5C
17	2	0.390	0.036	C17orf54
17	6	0.080	0.003	MPRIP
18	2	0.450	0.038	PTPRM
19	2	0.295	0.002	GNA15
20	2	0.100	0.000	RP5-1022P6.2
21	2	0.490	0.001	ERG

Core regions that do not contain a known gene are not listed.
*Genes are listed for the core region only and not the 500 kb extended haplotype regions identified by each core.

ISSN: 1479-7364