Figure 2
From: Maternal transmission of Alzheimer's disease: Prodromal metabolic phenotype and the search for genes
Statistical parametric maps showing reduced brain glucose metabolism in cognitively normal individuals with a maternal history of AD (FHm) compared with those with a paternal history of AD (FHp, in red) and with those with no family history of AD (FH-, in green) [7]. Brain regions showing hypometabolism in FHm compared with FHp and FH- include the inferior parietal lobes, lateral and inferior temporal cortex, posterior cingulate/precuneus and dorsolateral prefrontal cortex. These same brain regions are typically hypometabolic in clinical AD patients. Figure shows the superior, posterior, right and left lateral views of a three-dimensional volume-rendered MRI.