Table 1 List of all human and mouse MMPs, with MMP number, trivial name, grouping by domain composition, grouping by phylogenetic alignment and chromosomal location.
From: Update of human and mouse matrix metalloproteinase families
| Â | Â | Group | Â | Mouse | ||
|---|---|---|---|---|---|---|
MMP # | Trivial name | Domain | Phylogeny | Human Chromosome | Orthologue | Chromosome |
MMP1 | Interstitial collagenase | Collagenases | A | 11q21-q22 | MMP1a, 1b | 9 |
MMP8 | Neutrophil collagenase | Collagenases | A | 11q21-q22 | MMP8 | 9 |
MMP13 | Collagenase 3 | Collagenases | A | 11q22.3 | MMP13 | 9 |
MMP2 | Gelatinase A | Gelatinases | A | 16q13-q21 | MMP2 | 8 |
MMP9 | Gelatinase B | Gelatinases | A | 20q12-q13 | MMP9 | 2 |
MMP7 | Matrilysin 1 | Matrilysins | A | 11q21-q22 | MMP7 | 9 |
MMP26 | Matrilysin 2 | Matrilysins | A | 11p15 | Â | Â |
MMP3 | Stromelysin 1 | Stromelysins | A | 11q22.3 | MMP3 | 9 |
MMP10 | Stromelysin 2 | Stromelysins | A | 11q22.3 | MMP10 | 9 |
MMP11 | Stromelysin 3 | Stromelysins | B | 22q11.23 | MMP11 | 10 |
MMP14 | MT1-MMP | Membrane TM | B | 14q11-q12 | MMP14 | 14 |
MMP15 | MT2-MMP | Membrane TM | B | 16q13 | MMP15 | 8 |
MMP16 | MT3-MMP | Membrane TM | B | 8q21 | MMP16 | 4 |
MMP24 | MT5-MMP | Membrane TM | B | 20q11.2 | MMP24 | 2 |
MMP17 | MT4-MMP | Membrane GPI | B | 12q24.3 | MMP17 | 5 |
MMP25 | MT6-MMP | Membrane GPI | B | 16p13.3 | MMP25 | 17 |
MMP12 | Macrophage elastase | Other | A | 11q22.3 | MMP12 | 9 |
MMP20 | Enamelysin | Other | A | 11q22.3 | MMP20 | 9 |
MMP27 | - | Other | A | 11q24 | MMP27 | 9 |
MMP19 | - | Other | C | 12q14 | MMP19 | 10 |
MMP21 | - | Other | C | 10q26.3 | MMP21 | 7 |
MMP23B | CA-MMP | Other | D | 1p36.3 | MMP23B | 4 |
MMP28 | Epilysin | Other | C | 17q21.1 | MMP28 | 11 |