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Figure 1 | Human Genomics

Figure 1

From: Inter-chromosomal variation in the pattern of human population genetic structure

Figure 1

Schematic presentation of single nucleotide polymorphism (SNP) mining, multivariate chromosomal and population diversity and network analysis strategies. There are ~3.7 million SNPs in the HapMap data release. Genotypes were summarised for each population. For each dataset, the number of alleles per locus (SNP) was coded to a string of numbers to obtain a full design matrix of alleles (the cells give the number of copies of each major allele for each individual: 0, 1 or 2). Two criteria were used to filter the SNPs included in the analysis: (i) locus call rate ≥ 95 per cent (ie we excluded all SNPs with more than 5 per cent missing data); and (ii) the SNP should be shared among populations, so that the same sets of SNPs were used throughout in the population comparisons. From the total of ~3.7 million SNPs in the HapMap data release, only 809,624 SNPs were eligible for analysis.

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