Stop codon type | Proportion of stop codons harbouring nonstop mutations causing human genetic disease (%)a | Proportion of stop codons in HGMD control gene sequences (%)b | Estimated proportion (number) of stop codons in the human genome (%)c |
---|---|---|---|
TAA | 26.05 | 28.60 | 27.8 (8106) |
TAG | 16.81 | 21.99 | 23.6 (6901) |
TGA | 57.14 | 49.40 | 48.6 (14203) |