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Table 3 Frequency of nucleotides present in regions flanking the mutated TAA stop codon (N = 40).

From: A meta-analysis of single base-pair substitutions in translational termination codons ('nonstop' mutations) that cause human inherited disease

Base

-6

-5

-4

-3

-2

-1

1

2

3

4

5

6

A

14

13

7

10

10

5

17

6

11

7

18

11

C

7

9

15

10

13

13

9

10

12

13

9

14

G

8

10

11

5

12

12

11

15

9

9

7

8

T

11

8

7

15

10

10

3

9

8

11

6

7

  1. Position 0, corresponding to the stop codon, is not shown. Nucleotide frequencies that are significantly higher/lower (p < 0.01) in comparison with the HGMD control dataset are shown underlined
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Human Genomics

ISSN: 1479-7364