From: Analysis of pharmacogenetic traits in two distinct South African populations
 |  |  |  |  | MAF | ||
---|---|---|---|---|---|---|---|
Gene | Haplotypes | Xhosa | CMA | pValue | |||
SLC22A6 | rs6591722 | rs4149170 | rs12293966 | rs955434 | Â | Â | Â |
 | T | G | A | G | 0.467 | 0.514 | 0.370 |
 | T | A | A | A | 0.233 | 0.199 | 0.460 |
 | T | A | G | G | 0.192 | 0.051 | 0.000 |
 | A | G | A | G | 0.082 | 0.147 | 0.091 |
CYP2C18 | rs7085563 | rs11188067 | rs2860840 | rs1326830 | Â | Â | Â |
 | T | A | G | C | 0.448 | 0.496 | 0.310 |
 | A | A | G | C | 0.403 | 0.258 | 0.003 |
 | T | G | G | C | 0.143 | 0.087 | 0.095 |
CYP3A4 | rs2738258 | rs7801671 | rs2740574 | rs7811025 | Â | Â | Â |
 | G | A | G | G | 0.127 | 0.290 | 0.003 |
 | G | A | G | A | 0.227 | 0.092 | 0.008 |
 | A | C | G | G | 0.180 | 0.084 | 0.014 |
 | G | A | A | G | 0.144 | 0.150 | 0.019 |
 | G | C | A | G | 0.049 | 0.224 | 3.30E-05 |
 | A | A | G | G | 0.100 | 0.079 | 0.140 |
 | A | A | G | A | 0.076 | 0.007 | 0.003 |
UGT1A1 | rs8330 | rs4148329 | rs1500482 | rs4663972 | Â | Â | Â |
 | G | A | A | A | 0.206 | 0.417 | 3.00E-05 |
 | G | G | A | G | 0.247 | 0.082 | 5.40E-05 |
 | G | G | A | A | 0.151 | 0.223 | 0.091 |
 | C | G | G | G | 0.183 | 0.156 | 0.520 |
 | C | G | A | A | 0.201 | 0.119 | 0.052 |
 | rs2003569 | rs887829 | rs28900396 |  |  |  |  |
 | G | A | A |  | 0.353 | 0.365 | 0.820 |
 | G | G | A |  | 0.129 | 0.330 | 5.20E-06 |
 | A | G | A |  | 0.177 | 0.154 | 0.640 |
 | A | G | G |  | 0.189 | 0.054 | 0.000 |
 | G | G | G |  | 0.149 | 0.094 | 0.110 |