Skip to main content

Table 2 Inferred haplotypes in the Xhosa and CMA populations

From: Analysis of pharmacogenetic traits in two distinct South African populations

     

MAF

Gene

Haplotypes

Xhosa

CMA

pValue

SLC22A6

rs6591722

rs4149170

rs12293966

rs955434

   
 

T

G

A

G

0.467

0.514

0.370

 

T

A

A

A

0.233

0.199

0.460

 

T

A

G

G

0.192

0.051

0.000

 

A

G

A

G

0.082

0.147

0.091

CYP2C18

rs7085563

rs11188067

rs2860840

rs1326830

   
 

T

A

G

C

0.448

0.496

0.310

 

A

A

G

C

0.403

0.258

0.003

 

T

G

G

C

0.143

0.087

0.095

CYP3A4

rs2738258

rs7801671

rs2740574

rs7811025

   
 

G

A

G

G

0.127

0.290

0.003

 

G

A

G

A

0.227

0.092

0.008

 

A

C

G

G

0.180

0.084

0.014

 

G

A

A

G

0.144

0.150

0.019

 

G

C

A

G

0.049

0.224

3.30E-05

 

A

A

G

G

0.100

0.079

0.140

 

A

A

G

A

0.076

0.007

0.003

UGT1A1

rs8330

rs4148329

rs1500482

rs4663972

   
 

G

A

A

A

0.206

0.417

3.00E-05

 

G

G

A

G

0.247

0.082

5.40E-05

 

G

G

A

A

0.151

0.223

0.091

 

C

G

G

G

0.183

0.156

0.520

 

C

G

A

A

0.201

0.119

0.052

 

rs2003569

rs887829

rs28900396

    
 

G

A

A

 

0.353

0.365

0.820

 

G

G

A

 

0.129

0.330

5.20E-06

 

A

G

A

 

0.177

0.154

0.640

 

A

G

G

 

0.189

0.054

0.000

 

G

G

G

 

0.149

0.094

0.110

  1. CMA, Cape Mixed Ancestry; MAF, minor allele frequency